James Deng
Associate Principal Scientist, Vaccine Analytical Research & Development Merck & Co
James Z. Deng is currently an associate principal scientist in Merck Research Laboratories, West Point, Pennsylvania. He brings over two decades of expertise in pharmaceutical discovery and development, with a recent focus on development analytical methods for vaccine development. He also worked on delivery of siRNA therapeutics and discovery of small molecule drugs, contributing significantly to these fields. He has co-authored more than twenty peer-reviewed publications and patent applications, reflecting his commitment to scientific excellence.
Seminars
Wednesday 8th April 2026
Roundtable Discussion: Designing Quality Control Strategies to Ensure Raw Material Purity to Minimize LNP Instability
12:00 pm
- How to effectively evaluate and verify raw material purity beyond vendor specifications?
- What quality control measures are essential for enzymes and excipients to ensure consistency and prevent LNP instability?
- How to develop effective screening strategies for raw materials that correlate impurity profiles with LNP stability and product performance?
Wednesday 8th April 2026
Analytical Characterization of Nanoparticles in Vaccine Development
2:00 pm
- Understanding how particle size, charge and molecular weight influence biodistribution, stability, and immunogenicity
- Leveraging SEC for the assessment of LNP homogeneity, aggregate detection, and encapsulation efficiency
- Applying DLS to characterize size distribution and polydispersity, and to monitor batch-to-batch consistency
NEW DATA
NEW COMPANY
