Fireside Chat: Bridging In Vitro/In Vivo Translation by Overcoming Limitations of Potency Assays & Animal Models to Accelerate Clinic Progress

2:30 pm - Tuesday 7th April 2026

  • What key factors should guide the selection of cell lines to develop bioassays that best predict in vivo LNP potency?
  • How to design quantitative assays that measure relevant payload expression levels for understanding biological activity?
  • Which animal models provide the most reliable assessment of LNP potency and how to better address variability in biodistribution and protein corona formation between species?

Speakers:

Principal Scientist, Biochemistry & Biophysics, Analytical Development
Sanofi
Chief Executive Officer
Abogen Biosciences