Panel Discussion: Overcoming Clinical Bottlenecks in LNP Development by Streamlining Processes for Advancing Safer Drug Products to Patients

  • What are the greatest technical challenges in translating LNP formulations from preclinic to human studies?
  • Given the complexity of LNP manufacturing, scale-up, and analytical characterization, what are the critical process and regulatory bottlenecks that currently slow clinical entry?
  • How can developers prioritize indications, optimize clinical trial design, and build CMC readiness to ensure more programs successfully reach patients?