Matt Eastwood
Scientist II, Nucleic Acid Delivery Novo Nordisk
Trained as a synthetic organic chemist at the University of Minnesota before transitioning to medicinal chemistry and now, the lipid nanoparticle field. I possess expertise in the design, synthesis, and characterization of new materials and new formulations of those materials.
Seminars
Wednesday 8th April 2026
Panel Discussion: Discussing Strategic Ligand Selection for a Variety of Targets to Gain Scalable & Potent Delivery
2:30 pm
- How to identify the most suitable targeting ligand modality for a specific target?
- How to effectively and uniformly integrate the ligand onto LNP formulations?
- How to ensure the chosen ligand is viable for large-scale manufacturing?
Monday 6th April 2026
Achieving Targeted LNP Uniformity by Incorporating Advanced Analytics for Ligand Quantification & Stability
10:30 am
Targeted LNPs are continuing to advance and evolve to enable extrahepatic targeting. However, they are hindered by limited robust analytical strategies. During this workshop deep dive into reliable analytical methods for assessing ligand density, stability and aggregation for more consistent product quality. Topics include:
- Leveraging comprehensive analytics to quantify ligand density to determine uniformity and minimize heterogeneity
- Unlocking advanced analytical strategies to understand ligand stability, linker degradation and free ligands for safer targeted LNPs
- Implementing imaging techniques for assessing aggregation, structural integrity and surface functionalization
