Shinichi Hashimoto
Head, LNP Formulation Discovery FUJIFILM Corporation
Seminars
Tuesday 7th April 2026
Novel Design of Ionizable Lipids & LNP Formulations for Nucleic Acid Delivery Leading to CAR Knock-In
2:00 pm
• Introduction of our proprietary ionizable lipid library in vivo
• Ready-to-use LNP for ex vivo studies
• Ex vivo Application-1: knock-out in human primary T cell
• Ex vivo Application-2: pDNA delivery to human primary T cell
• In vivo Application: extra-hepatic lipids which were found from ex vivo studies
