Pre-Conference LNP 101 Day: Monday, April 29, 2024
9:15 am Chair’s Opening Remarks
9:30 am Introducing LNPs as the Future of Drug Delivery to Establish Context of the Developments to Date
Synopsis
- Overviewing the history of LNPs to appreciate the rapid development of the delivery vehicle
- Sharing the basic mechanisms of LNPs to reaffirm the structural and functional properties
- Highlighting the key bottlenecks throughout LNP development currently being addressed throughout industry and academia
10:15 am Evaluating the Current State of Play in 2024 to Convey the Key Priorities for LNP Development
Synopsis
- Considering the necessary steps to advance more LNP drug products through to the clinic
- Spotlighting the current disease indications accessible for LNPs as well as the gaps currently unreachable
- Reviewing the breadth of drug substances currently delivered within LNPs, as the field moves beyond mRNA
11:00 am Morning Break
12:00 pm Honing the Fundamental LNP Components to Provide Clarity for What Is Required to Formulate a Functional LNP
Synopsis
- Exploring the 4 key lipids within an LNP and their role to support functionality
- Enlightening the role of conjugates and surface markers in the delivery of LNP to target organs
- Understanding the dynamic of lipid components and the payload to assure stability of formulation
12:30 pm Reflecting on the Design & Development of LNP Delivery Platforms for Nucleic Acid Therapeutics
Synopsis
- Revealing industrial perspective on discovery and development of nanomedicines specific for diseases
- Considering design, characterization and translation across species
- Reviewing the opportunities for next generation delivery systems
1:00 pm Lunch & Networking
2:00 pm Roundtable Discussion: Evaluating the Progress Made by Biopharma, Biotech & Academia & the Hurdles Still to Overcome
Synopsis
- Collaborating to establish what the LNP field are currently excelling in and significant success stories of 2024
- Accepting areas of focus to drive more LNP products closer to commercialization
- Benchmarking phase to phase success to outline realistic roadmap from concept to clinic
3:00 pm Speaker Q&A
Synopsis
Have your burning questions answered by the expert speaker panel to help strengthen your grasp on the latest LNP advancements